I have hit the jackpot with one store in particular located in more of an "upscale" town nearby. Today I came away loaded with all sorts of brand name loot (Gap, Eddie Bauer, Anne Taylor Loft, Tommy Hilfiger, etc.) for far less than I would have paid in the department stores. The find of the day was my "new to me" grey, hoodie cashmere sweater for $18. Oooh, it's so soft!
I don't buy everything second hand because frankly its a bit of a crapshoot whether you will find what you are looking for or not from one visit to the next. Patience and repeat visits are key since the selection is so variable.
These are some of my consignment store finds from a few months ago. Lucky Jeans, Anne Taylor work pants and American Eagle Outfitters skirt.